Among them, E1, E2 and E4 are regulatory genes involved in transcription and replication, E5, E6 and E7 are potential oncogenes, L1 and L2 are two genes encoding self-assembling proteins that produce viral capsids. PVs contain early genes (E1-E8) encoding nonstructural proteins and late genes (L1 and L2) encoding structural proteins, and the open reading frames (ORFs) arrangement of viruses in different animal species is different. At present, numerous identified non-human papillomaviruses (NHPs) have been identified in a wide range of animals including cattle, dogs, pigs, domestic cats, manatees, giant pandas, and cetaceans, and they are commonly reported to be associated with mucosal and cutaneous lesions.
Geneious prime database skin#
However, there are several studies that have identified PVs in healthy skin and mucous membranes.
Papillomaviruses (PVs) are capable of infecting the skin and mucosal surfaces of mammals and many other vertebrates in a host-specific manner and can cause papilloma or fibromyoidoma in humans, animals, and birds. Members of the family Papillomaviridae are non-enveloped, small, circular viruses with double-stranded (ds) DNA genomes of approximately 5.7 to 8.6 kilobases (kb) in size. Due to the rapid development and wide application of sequencing technology in recent years, more and more novel viruses have been continuously identified, and the host species population of known viruses has also increased rapidly.
0 kommentar(er)
